[Jacob-list] Genetic testing =Scrapie ?

[Jacobflock at aol.com]

In a message dated 3/12/2003 1:10:09 PM Central Standard Time, 
RnS1260 at aol.com writes:

> Has any one ever done 
> genetic testing on their ewes to see if they are predisposed to Scrapie? If 
> 
> so is the testing costly? What lab would it be sent to, or is this 
> something 
> ones vet determines?
> 

Genetic testing of rams makes more sense than testing all ewes.  There are 
three codons 171, 154 and 136 that appear to be involved with scrapie.  One 
source for the test is GeneCheck, Ft.Collins, CO USA ... about $20 for codon 
171, 3about $30 for 171 and 136, about $50 for all three.  

The test is also available thru Guelph but don't know the cost.

Normally an RR at 171 suggest low suseptability and an RR will have an A at 
136.  There is some concern because a Japanese? sheep with RR and AA? at 136 
had a form of scrapie.

In England testing for the three codons suggested that hill breeds (including 
Jacobs) had a lower suseptability compared to down breeds but cases have been 
reported in Jacobs ... and Soay (primitive type).

Fred Horak
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