[AGL] Fw: Old miracle drug rediscovered
michele mason
yaya.m at earthlink.net
Wed Nov 1 19:59:21 EST 2006
Thanks Gerry. I've been away from the screen with heavy focus work and
I'm just now catching the thread again. Its kind of like waking at the
end of the day. I'm sure I'll see my pillow soon. I'm a morning person
for sure. I'll check on that. I've used Puritan for years and its been
really helpful, but haven't compared. Thanks again, mm
On Oct 31, 2006, at 6:46 PM, Gerry wrote:
> Michelle,
> A good online source for supplements is iherb.com. I ordered Beta
> Glucan from them, the NOW brand which I have found to be of consistent
> high quality.
> G
>> ----- Original Message -----
>> From: Michele Mason
>> To: survivors' reminiscences about Austin Ghetto Daze in the 60s
>> Sent: Tuesday, October 31, 2006 5:18 PM
>> Subject: Re: [AGL] Fw: Old miracle drug rediscovered
>>
>> Bill, Sounds very good and somewhere in here is where to get it? Too
>> tired to search. Thank-you for meaningful help as always mm
>>
>> On Oct 31, 2006, at 1:58 PM, Bill Irwin wrote:
>>
>>> Note: I am fowarding this on to your list Mike because I think it is
>>> some thing everyone should know about. Also, I think Wayne should
>>> be taking this and I would be interested in hearing what Gerry would
>>> have to say about this.
>>>
>>>
>>>
>>>
>>> The upcoming memorial to Billy Jim makes me think that some things
>>> can be done to protect against cancer. With this thought in mind I
>>> would like to introduce to the ghetto folks a nutraceutical that can
>>> do much to enhance the immune system and to protect us against
>>> cancer and a host of other problems. You may not have heard of it
>>> before as knowledge of its benefits is not that old and it is not
>>> that available in the stores. That substance is Beta Glucan. It is
>>> found in oat meal and is responsible for all the advertising
>>> proclaiming the healthful aspects of oats which is all true. It is
>>> also found in other foods but in lesser amounts. It is also found
>>> in abundance in the Japanese Maitake mushrooms which have been used
>>> to prevent and treat cancer for a long time. The beta glucan you
>>> buy in health food stores has three major sources - extracted from
>>> oats, extracted from the Maitake mushroom, or made from the
>>> breakdown of the cell walls of a nutritional yeast. As far as I can
>>> tell they are all about the same. This nutraceutical has so many
>>> health benefits that I think everyone should know about it and be
>>> taking it for their own health and protection against cancer and
>>> other infections. So I am going to give the complete low-down on
>>> beta glucan and why you should be using it.
>>>
>>> This is important so pay attention. The reading list is difficult
>>> but worth the effort.
>>>
>>> Beta glucan is a polysaccharide (long chain sugar) molecule with
>>> important branches at certain positions. You may see it labeled as
>>> Beta-1,3/1,6 -D-Glucan - meaning it has branches at the 1,3 position
>>> and the 1,6 position. It plays a very critical role in the immune
>>> system. Macrophages, the white blood cells that go around the body
>>> and attacks germs, cancers, and foreign antigens, they can destroy
>>> cancer cells and eat them for breakfast, same for germs.
>>> Macrophages have attachment sites on the outside of the cells for
>>> beta glucans. The more beta glucan that attaches to the macrophages
>>> the more aggressive they become in attacking cancers and germs.
>>> They also produce more tumor necrosis factor, TNF, which is a
>>> compound that can kill cancer cells. They also produce
>>> more Interleukin-2 which activates and stimulates the growth of
>>> immune cells, most importantly T-Cells, but also Natural Killer
>>> Cells , both of which are capable of destroying cancer cells
>>> directly. Macrophages are some of the first white blood cells to
>>> appear at the site of a physical wound as part of their job is to
>>> also eat up dead cell tissues and catch germs that enter the wound.
>>> Beta glucan is probably the best stimulant of the immune system
>>> that you could find. Some other cells have attachment points for
>>> beta glucan, most notably dermal fibroblast cells which do much of
>>> the work in making new skin - more on this later.
>>>
>>> For a good paper on immune system deficiencies, their causes,
>>> symptoms, what can be done about it and the use of beta glucan see
>>> this reference - http://www.immunocorp.com/ca/research.pdf A lot
>>> of good information and you should read it, moderately difficult.
>>> It makes the case for immune system repair.
>>>
>>> Much is made of the use of beta glucan to treat cancer. Countless
>>> studies have been made and all say that beta glucan is an aid to
>>> cancer treatment. The use of mushrooms to treat cancer has long
>>> been known in Asia. Here is a good paper on the use of mushroom
>>> beta glucans to treat cancer -
>>> http://www.thorne.com/altmedrev/fulltext/cancer5-1.html Beta glucan
>>> when taken in conjunction with chemo agents enhance the effects of
>>> chemo and reduce its bad effects. It's 1+1= 2.5 or more and you get
>>> less sick from the chemo. Numerous case histories also show where
>>> beta glucan cured the cancer and in most every case the cancer was
>>> slown down. Works best with chemo but can work on a daily basis to
>>> prevent the rise of cancer cells at a very early stage. Here is a
>>> report on the use of mushroom extracts to treat cancer patients with
>>> many case histories -
>>> http://www.thorne.com/pdf/journal/7-3/maitake_md_fraction.pdf
>>>
>>> Another good paper is this one on the use of mushroom beta glucans
>>> to treat cancer and also discusses beta glucan to treat diabetes,
>>> hypertension, cholesterol, and a few other conditions.
>>> http://www.thorne.com/pdf/journal/6-1/maitake_mxtract.pdf
>>>
>>> You have seen countless ads on TV about how farmer John's oat cereal
>>> is the cereal for healthy hearts. It will reduce cholesterol, and
>>> blood pressure which is all true. Farmer John didn't tell you that
>>> you would have to eat 2 or 3 bowls three times a day to get a
>>> therapeutic dose to treat a condition, but as a preventative measure
>>> it is a good place to start. Many studies have been made and they
>>> all show that beta glucan from oat meal will lower cholesterol and
>>> blood pressure over time. The reductions are not great but for many
>>> people it could mean the difference between a problem and being OK.
>>> If you need significant improvements quickly due to a health threat
>>> the pharmaceutical will give stronger action but with more side
>>> effects. The higher the beta glucan content the bigger the
>>> improvement. See the links below for references to hypertension and
>>> cholesterol studies that have been done.
>>>
>>> If you have type 2 diabetes beta glucan may be of some help.
>>> Several studies have been made on the effect of beta glucan on this
>>> type of diabetes and they all show that you can expect a decline in
>>> blood sugar and blood insulin. I am not an expert in diabetes but I
>>> would think that this might be of some help in reducing symptoms and
>>> long term side effects of type 2 diabetes. The same effect of
>>> lowering blood sugar and insulin also works on people who have
>>> normal sugar metabolism meaning that it may help people that are in
>>> danger of developing type 2 diabetes. This is not a cure of
>>> diabetes, only a help in dealing with the problem. See the
>>> reference links below for results of these experiments.
>>>
>>> In other promising studies beta glucan was given to patients that
>>> were to have high risk abdominal surgeries to see if it could
>>> prevent later complications. Patients who received beta glucan
>>> treatment prior to surgeries have fewer infections, less server
>>> infections, and fewer post operative complications resulting in
>>> shorter stays in intensive care units. One study reported a 39%
>>> decrease in infections and deaths in patients who received beta
>>> glucan. These results are supported in studies where rats given
>>> beta glucan and then had experimental wounds and surgeries had
>>> faster wound healing, the wounds developed higher tensile strength
>>> earlier, and in many case prevented infections in rats. The treated
>>> rats had a much higher survival rate and fewer complications. If
>>> you are going to have a major surgery you should start taking beta
>>> glucan about a week before surgery and continue until full
>>> recovery. I can't help to think that Clark Santos might still be
>>> here if he had been taking this supplement prior to his emergency
>>> room trip. Once again, see the references below.
>>>
>>> One of the more interesting aspects of beta glucan is its activity
>>> in regenerating skin. It can stimulate dermal fibroblasts to make
>>> more collagen which will make skin a little thicker and help to
>>> erase fine lines and wrinkles. Numerous studies have shown that
>>> beta glucan can improve wound healing, make the wound healing
>>> process stronger and faster. Thicker skin and fewer wrinkles sounds
>>> like something that the older ghetto residents might be interested
>>> in. It was also of some interest to the cosmetics industry and they
>>> did a scientific study of the question and found that beta glucan
>>> applied to the skin can penetrate the skin and stimulate the
>>> fibroblast to make more collagen and the result is improved skin
>>> condition with fewer wrinkles. Their study has microscopic proof of
>>> its action and data to support the claim to improved condition.
>>> Their study was based on a 8 week treatment with beta glucan so it
>>> is not a quick fix.
>>>
>>> International Federation of Societies of Cosmetic Chemists report:
>>> http://www.ceapro.com/pdfs/ifscc.pdf
>>>
>>> Oat (1,4; 1,3) beta-glucan is a natural active ingredient offering
>>> significant performance enhancing properties for personal care
>>> applications. Our studies have shown that the molecule, despite its
>>> considerable molecular weight, is able to enter the stratum corneum
>>> and epidermis and penetrate deep into the dermis. The observed
>>> effects of beta-glucan on tissue restructuring and wrinkle reduction
>>> are most likely effects mediated by fibroblast stimulation and
>>> collagen deposition in the dermis. These unique properties make oat
>>> beta-glucan a promising and effective ingredient for cosmetics.
>>>
>>> I have been taking it for about 2 months and have noticed an
>>> improvement in my skin similar to the cosmetics industry report. I
>>> also credit it with curing a skin condition that I had. It seems to
>>> me that oral intake has the same skin improvement effects and does
>>> all the other good things that beta glucan can do so I think that is
>>> the best route. Some cosmetic products are already appearing on the
>>> market with beta glucan. Or, maybe you can have your lover massage
>>> you every night with hot oat meal.
>>>
>>> In summary:
>>>
>>> WHAT CAN BETA GLUCAN DO FOR YOU
>>> Strengthen your immune system by filling attachment points on
>>> macrophages thereby making them more aggressive
>>> Enables your immune system to better kill cancer cells
>>> Enables your immune system to better kill germs
>>> Slows the growth of cancers and in a few exceptional cases has cured
>>> cancers
>>> Works with chemo to make it stronger and reduces side effects from
>>> chemo
>>> Will give modest reductions in cholesterol
>>> Will give modest reductions in hypertension
>>> Type 2 diabetics may have lower glucose and insulin levels
>>> Surgery patients have fewer deaths, infection, and complications
>>> All wounds heal faster, better, and stronger
>>> Reduces fine lines in skin
>>> Makes your skin look younger
>>> Now, can anybody find some negative in this list? What we are
>>> talking about is some extract from oat meal. Oat meal is not a
>>> dangerous substance, I did not see any report on side effects in the
>>> many reports I have read on this substance. You need less than a
>>> 1/2 gram of this oat concentrate a day to get most of these
>>> protective effects, much more if you are headed to the operating
>>> room or have active cancer.
>>>
>>> About the dosage: For maintenance from 200-400 mg a day. I am
>>> taking 200 a day but think I could use a little more so I plan on
>>> going to 300 mg a day. For pre-operative protection take 1500 mg a
>>> day for a week before, then 500mg a day until you feel that you
>>> recovered completely from the surgery, then back to maintenance
>>> dose. For active cancer 1500 mg or more plus a complete set
>>> nutraceuticals aimed at fighting cancer, there are several good
>>> books on this subject. Vitamin D is involved with beta glucan and
>>> the immune system so you need to be sure you have enough - take
>>> 400-800 IU depending on your diet and how much time you spend in the
>>> sun.
>>>
>>> Why I am writing this letter: I am tired of hearing about Billy
>>> Jim, Clark Santos, Jaxon, just to name a few of the recent ones, who
>>> could have had their lives extended or maybe even found cures if
>>> they only had known about this simple substance. Now I have
>>> passed the information on to all of you and you can no longer plead
>>> ignorance. Please take care of yourself dear folk.
>>> Aloha,
>>> Ewie
>>>
>>> ******************************
>>>
>>> The references: These are mostly in the form of abstracts which
>>> are difficult to read as the whole research project is condensed in
>>> one paragraph. Generally the first sentence or two has the theses
>>> and the last sentence the results and a lot of big words in between.
>>>
>>> Hypertension
>>> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
>>> cmd=Retrieve&db=PubMed&list_uids=7956987&dopt=Abstract
>>> lowered cholesterol and LDL but not HDL
>>>
>>> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
>>> cmd=Retrieve&db=PubMed&list_uids=11978262&dopt=Citation
>>> RESULTS: The oat cereal (cereal enriched with beta glucan -
>>> 5.52%) group experienced a 7.5 mm Hg reduction in SBP (P <.01) and
>>> a 5.5 mm Hg reduction in DBP (P <.02), while there was virtually
>>> no change in either SBP or DBP in the control group. In the oat
>>> cereal group, a trend was observed for a lower total insulin
>>> response to a glucose load, suggesting improved insulin sensitivity.
>>> However, this could not be confirmed using estimates from the
>>> Bergman Minimal Model, perhaps because of our small sample size. The
>>> oats group experienced a significant reduction in both total
>>> cholesterol (9%) and low-density lipoprotein cholesterol (14%).
>>> CONCLUSIONS: The addition of oat cereals to the normal diet of
>>> patients with hypertension significantly reduces both SBP and DBP.
>>> Soluble fiber-rich whole oats may be an effective dietary therapy in
>>> the prevention and adjunct treatment of hypertension.
>>>
>>> http://intl.jacn.org/cgi/content/abstract/16/1/46
>>> Effect of beta-glucan level in oat fiber extracts on blood lipids in
>>> men and women
>>> Total cholesterol levels after the higher beta-glucan extract diet
>>> were significantly lower than those after the low beta-glucan diet.
>>> CONCLUSIONS: Beneficial reduction of cholesterol was obtained with
>>> modest amounts of oat extract incorporated into the diet. A
>>> significant dose response due to beta-glucan concentration in the
>>> oat extract was observed in total cholesterol levels.
>>>
>>> Diabetes
>>> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
>>> cmd=Retrieve&db=PubMed&list_uids=8033532&dopt=Citation
>>> A diet rich in beta-glucan may therefore be of benefit in the
>>> regulation of postprandial plasma glucose levels in subjects with
>>> Type 2 diabetes.
>>>
>>> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
>>> cmd=Retrieve&db=PubMed&list_uids=8948386&dopt=Citation
>>> Oat bran concentrate bread products improve long-term control of
>>> diabetes: a pilot study. CONCLUSIONS: The well-accepted oat bran
>>> concentrate bread products improved glycemic, insulinemic, and
>>> lipidemic responses.
>>>
>>>
>>>
>>> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
>>> cmd=Retrieve&db=PubMed&list_uids=11874441&dopt=Citation
>>> Effects of a water-soluble extract of maitake mushroom on
>>> circulating glucose/insulin concentrations in KK mice. CONCLUSIONS:
>>> FXM, a natural extract obtained from maitake mushroom, favourably
>>> influences glucose/insulin metabolism in insulin-resistant KK mice.
>>> The lowering of both circulating glucose and insulin concentrations
>>> suggests that FXM works primarily by enhancing peripheral insulin
>>> sensitivity.
>>>
>>> Cancer
>>> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
>>> cmd=Retrieve&db=PubMed&list_uids=10851301&dopt=Citation
>>> A bioactive beta-glucan from the Maitake mushroom has a cytotoxic
>>> effect, presumably through oxidative stress, on prostatic cancer
>>> cells in vitro, leading to apoptosis.
>>>
>>> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
>>> cmd=Retrieve&db=PubMed&list_uids=8575861&dopt=Citation
>>> In the established tumor model, beta glucan + BsAb reduced the
>>> incidence of s.c. tumors as compared with control, with BsAb alone
>>> and with beta glucan alone. It also prolonged survival of
>>> tumor-bearing mice compared with control, BsAb alone and beta glucan
>>> alone. We conclude that T cells can be activated in vivo by beta
>>> glucan and retargeted with F(ab')2 BsAb.
>>>
>>> Surgery
>>> http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1234447
>>> PGG-glucan is safe and appears to be effective in the further
>>> reduction of the morbidity and cost of major surgery.
>>>
>>> http://archsurg.ama-assn.org/cgi/content/abstract/134/9/977
>>> Conclusion Perioperative administration of PGG-glucan reduced
>>> serious postoperative infections or death by 39% after high-risk
>>> noncolorectal operations.
>>>
>>> http://www.springerlink.com/content/egx2ddc85e7fj98t/
>>> Inguinal hernia repair with beta glucan-coated mesh: results at
>>> two-year follow up - hernia repair with beta-glucan coated mesh has
>>> a low recurrence rate. Incidence of chronic pain is low. The
>>> situation is in relationship with a lightweight and smooth mesh of
>>> polypropylene and the role of oat beta glucan optimizing the healing
>>> and inclusion of the mesh into the tissues.
>>>
>>> Wound healing
>>> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?
>>> cmd=Retrieve&db=PubMed&list_uids=9012425&dopt=Citation
>>> These data indicate that macrophage modulation with glucan phosphate
>>> will increase tensile strength in experimental colon and skin
>>> wounds. In addition, we observed a positive correlation between
>>> glucan phosphate treatment, wound tensile strength, and collagen
>>> biosynthesis.
>>>
>>> Skin
>>> http://www.blackwell-synergy.com/links/doi/10.1046/j.1524
>>> -475X.2002.10804.x/abs/
>>> Glucan stimulates human dermal fibroblast collagen biosynthesis
>>> through a nuclear factor-1 dependent mechanism
>>>
>>>
>>> Protection against infection:
>>>
>>> http://www.blackwell-synergy.com/doi/abs/10.1111/j.1574
>>> -695X.2000.tb01420.x
>>> The data demonstrate that SSG administered systemically protects
>>> against pneumococcal infection in mice.
>>>
>>> http://www.springerlink.com/content/k35n277mq8680340/
>>> Conclusions In this rat model of intra-abdominal sepsis
>>> <xxlarge946.gif>-glucan treatment partially protected against
>>> secondary lung injury, decreased lung hemorrhages, and lung
>>> neutrophilia. These results suggest that <xxlarge946.gif>-glucan
>>> protects against sepsis-associated lung
>>> damage.<xxlarge946.gif><xxlarge946.gif>
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